Visitors to this page also searched for: Military urine check for maxalt. If the first RIZATRIPTAN WAFERS-10mg Wafer does help your migraine, but it comes back later, you may take another wafer. Your doctor will advise you about this if it is recommended for you. We comply with the HONcode standard for trustworthy health information -, https://www.drugs.com/cdi/sumatriptan-injection.html. Effective for the acute treatment of a migraine with or without aura in adults. from the best health experts in the business. You should refer to the prescribing information for sumatriptan for a complete list of interactions. Talk to your doctor or pharmacist before taking any other medication or herbal product that may interact with sumatriptan. If the initial sumatriptan dose has been given by injection, and the migraine returns, sumatriptan tablets may be administered at two-hour intervals up to a maximum cumulative tablet dose of 100mg/day. When taken as an oral tablet, acyclovir has a half-life of 2.5 to 3.3 hours in healthy adults. Registered in England and Wales. Triptans work by stimulating the receptors of a natural substance in the brain called serotonin (or 5HT). It usually takes around 24 hours for sildenafil to leave your bloodstream. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use sumatriptan only for the indication prescribed. Can Acid be detected in the blood or urine? This medicine is for you. Do not take more than 200mg of sumatriptan in a 24 hour period. How Long Do Shrooms Stay In Your System Referencing the Psychedelics Encyclopedia by Peter Strafford, 80% of the metabolite is excreted in the first eight to twenty-four hours of use, but residual metabolites may be stored in fat and, depending on use, may be detectable for weeks. If you use rizatriptan long-term, your heart function may need to be checked using an The second dose must be administered at least two hours after the first dose. Medicines that interact with sumatriptan may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with sumatriptan. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Safety and effectiveness, when used for other headache disorders (such as cluster headache) has not been established. This eMedTV resource describes how the drug works, explains when and how to take it, and lists some of its potential side effects. Because sumatriptan works quickly and effectively, it may decrease the need for other pain-relieving medications and allow a person to quickly return to their normal routine. Tell your doctor all medications and supplements you use. What happens to your body when you come off the pill? Many migraine attacks occur for no apparent reason, but for some people there may be things which trigger an attack, like certain foods or drinks. Patient is a UK registered trade mark. I'm afraid I will test positive. antidepressants, such as citalopram, desvenlafaxine, duloxetine, fluoxetine, mirtazapine, or nefazodone, monoamine oxidase inhibitors, such as isocarboxazid, phenelzine, or selegiline, other migraine medications, such as dihydroergotamine, almotriptan, rizatriptan, or zolmitriptan, opioids, such as buprenorphine, codeine, fentanyl, oxycodone, methadone, morphine, or codeine. Continued For example, you can get sumatriptan ( Imitrex ) … Take rizatriptan exactly as your doctor tells you to. Why people with migraine should develop these chemical changes is also not clear. If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking. Medication-induced headache (also called medication-overuse headache) is caused by taking painkillers or triptans too often. If you have high blood pressure (hypertension). Your blood pressure may need to be checked often while you are using this medicine. Overall, I’m a healthy 31 year old female. Do not use this medicine for more than 10 days in any 30-day period, unless your doctor tells you to. Depending on the type of addiction, acute withdrawal typically occurs within a few hours of a person’s last dose. 1 , 4 Ambien is categorized as a non-benzodiazepine hypnotic medication. If you are taking a Maxalt® tablet, swallow the tablet with a drink of water. Ondansetron orally disintegrating tablet is used to prevent nausea and vomiting caused by certain medical treatments. Take the container with you, even if it is empty. SUMATRIPTAN clearly belongs in some of the indigestion or spoonful of inoculum. Symptoms of a stroke or TIA may be easily mistaken for those of a migraine. Sumatriptan may be used to relieve symptoms of a migraine. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Dated February 2018. Note down when and where each migraine attack started, what you were doing, and what you had eaten that day. How Long Do I Need To Stay Drug Free Of Maxalt Before I Try To Get Pregnant? Sumatriptan has been associated with an increased risk of stroke, hemorrhage or TIA; however, it is not clear whether this is due to the presence of migraine, or people mistaking stroke symptoms for those of a migraine. These sensations do not usually last for long, but if they continue or become intense, do not take any more tablets, and let your doctor know as soon as possible. Do not keep administering sumatriptan. COVID-19 coronavirus: what is an underlying health condition? If you have migraines frequently, discuss this with your doctor. USES: Rizatriptan is used to treat migraines Sumatriptan oral tablets usually start working within 30 minutes, with the peak effect occurring within two to four hours. If you have any problems with the way your liver works or with the way your kidneys work. Your chest may feel tight or 'heavy' after taking rizatriptan. Almost all patients who develop giant cell arteritis are over the age of 50. All rights reserved. Our clinical information is certified to meet NHS England's Information Standard.Read more. Rizatriptan belongs to a class of medicines known as 5HT1-receptor agonists. If you have any concerns at all that your symptoms may be those of a stroke, call 911 and seek immediate medical attention. The diagnosis of a migraine will need to be reconsidered if the migraine attack does not respond to the first dose of sumatriptan. There is a risk of serotonin syndrome developing if too high a dosage of sumatriptan is used or other drugs are taken that also increase serotonin levels in the body. How Long Does Opiate Withdrawal Last? Revised 03/2020. Although rizatriptan is better taken when your stomach is empty, you can still take it if you have had a meal. Tell your doctor if your condition does not improve or if it worsens. Do not take sumatriptan if you have previously had a stroke or TIA. It is rare for migraines to suddenly develop during adulthood; most people experience their first one in childhood. If your migraine at first improves but then comes back again, you may take another tablet/wafer, providing it is at least two hours after you took the first one. Upgrade to Patient Pro Medical Professional? Famciclovir has a half-life of 10 hours in HSV-1 infected cells and 20 hours in HSV-2 infected cells. "Some antibodies stay in the system for years..." 7 1 Some antibodies stay in the system for years, most last about one year. It does not help prevent migraine headaches from developing. Hey everyone!I was diagnosed what was thought to be Menieres Disease about 2 1/2 years ago. The information on this page is written and peer reviewed by qualified clinicians. A stroke tends to come on suddenly, whereas symptoms of a migraine with aura tend to evolve gradually over several minutes. Pradaxa (dabigatran) helps to prevent platelets in your blood from sticking together and f ... read more. This is a common occurrence and is usually not a sign of a heart problem. Medically reviewed by Carmen Fookes, BPharm. Dated February 2018. Some people may benefit from taking a non-steroidal anti-inflammatory painkiller (such as naproxen) in addition to rizatriptan. May interact with a number of different drugs including ergot-containing drugs and those that increase serotonin (such as antidepressants, St Johns Wort, and antipsychotics). Revision date: April 15, 2020. Drugs.com https://www.drugs.com/cdi/sumatriptan-injection.html. Before taking rizatriptan, tell your doctor if you are How long does oxy stay in your system.I am scheduled for a urine test soon. Sumatriptan may also be called a triptan. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If you have heart problems such as angina, or if you have had a heart attack. Rizatriptan can raise blood pressure to dangerous levels. In cells infected with herpes zoster, the drug had a half-life of 9 to 14 hours. Don't delay your care at Mayo Clinic Schedule your appointment now for safe in-person care. Talk to your doctor if you have had more than four episodes of a migraine in a 30-day period for which you have taken sumatriptan for. Sumatriptan. Bonine is an over-the-counter medication commonly used for treating and preventing motion sickness. You should not take other migraine treatments such as other triptans or ergotamine at the same time as rizatriptan. You may not realize your vision has been impaired with a stroke until you start bumping into things. Because the disease is relatively uncommon and because the disease can cause so many different symptoms, the diagnosis of GCA … Ask your pharmacist any questions you have about refilling your prescription. Speak to your doctor about how drug interactions should be managed. Liver disease can dramatically shorten the time it takes for sumatriptan to act and the length of time it lasts for in the body. The effects of the injection are usually apparent within 5 minutes. Is it safe to delay your period for your holiday? The effects of the injection are usually apparent within 5 minutes. Rizatriptan is meant to be used to treat headache pain during a migraine attack, not to stop the pain from coming on. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Available as an oral tablet, a nasal spray, a nasal powder for inhalation, and in an injectable form. If you are taking a Maxalt® Melt wafer, this has been made so that you can place it on your tongue and allow it to dissolve in your mouth. Overuse of sumatriptan and other acute migraine drugs may lead to medication overuse headache (symptoms include daily headaches or a marked increase in migraine frequency). The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Never take more than the prescribed dose. Does LSD Show Up On Drug Test? Higher dosages carry a greater risk of side effects. Sumatriptan belongs to the class of medicines known as selective serotonin receptor agonists. What do you think? Your blood pressure may need to be checked often while you are using rizatriptan. Guide to LSD Drug Testing! Do not take it before the headache begins (for example, during the 'aura phase'), as it may be less effective. For details see our conditions. Sumatriptan oral tablets usually start working within 30 minutes, with the peak effect occurring within two to four hours. How long does Sildenafil stay in your system? Maxalt (Rizatriptan Benzoate) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Drowsiness or dizziness, fatigue, tingling or numbness in the fingers or toes, or a feeling of weakness. Giant cell arteritis (GCA) is the most common form of vasculitis that occurs in adults. If you are taking or using any other medicines. Available for Android and iOS devices. How long ahve you been taking aspirin 325 jeg slap nogenlunde afsted med at arming ned til kunderne . PsychedelicsDaily sheds light on Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. In most people, sumatriptan works quickly, within 5 minutes for the injection or within 10 to 20 minutes with the tablets. If you have ever had a stroke or a transient ischaemic attack (this is also referred to as a TIA, or 'mini-stroke'). Coronavirus: what are moderate, severe and critical COVID-19? What could be causing your pins and needles? Coronavirus: what are asymptomatic and mild COVID-19? Taking it earlier in a migraine attack will not stop the headache from developing. Sumatriptan should also not be taken by people with a history of hemiplegic or basilar migraine, ischemic bowel disease, severe hepatic impairment, or who have recently taken certain medicines including ergotamine derivatives and monoamine oxidase inhibitors. I took 2 Ambien (zolpidem) 10 mg yesterday at 4 PM. Select one or more newsletters to continue. You will find a full list in the manufacturer's information leaflet supplied with your medicine. However, its effect will gradually lessen as the drug is broken down by your body. Skeletal muscle relaxants may cause the functions of your central nervous system (CNS) to slow down, leading to CNS depression. View complete list of side effects. A few years ago, when the symptoms first started, I was working... Assess your symptoms online with our free symptom checker. There are four stages of withdrawal from opiates: anticipatory, early acute, fully-developed acute, and post acute withdrawal syndrome (PAWS). Sumatriptan is not suitable for people with certain cardiovascular conditions including coronary artery disease, Prinzmetal’s angina, Wolff-Parkinson-White syndrome, a history of stroke or transient ischemic attack (TIA), uncontrolled high blood pressure, or peripheral vascular disease. If you are aged over 65 years or under 18 years. Like benzodiazepines, Ambien acts on receptor cells in the brain that bind with GABA (gamma-aminobutyric acid), a brain chemical that influences sleep and other neurological activities. Manufacturer's PIL, Maxalt® 5 mg and 10 mg Tablets; Merck Sharp & Dohme Limited, The electronic Medicines Compendium. If you develop symptoms suggestive of serotonin syndrome, discontinue sumatriptan and talk to your doctor straight away. Rizatriptan is effective in relieving migraine attacks once the headache phase has started. I was able to stay off of Maxalt for about a month and then I started to get migraines on a daily basis. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Become a COVID-19 treatment pioneer today. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. How Long Does Ambien (Zolpidem) Stay In Your System? Maxalt® Melt wafers are particularly helpful if drinking water to take a tablet would make you feel sick. Do not drive or operate machinery or perform other hazardous tasks if a migraine or its treatments make you drowsy. If you feel much better after a dose of rizatriptan, but your headache comes back or gets worse after a while, adults may use one additional dose of rizatriptan 2 hours after the first dose. It is usual to take one tablet as soon as you start to feel a migraine headache develop. It may help to keep a migraine diary. For these reasons, before you start taking rizatriptan it is important that your doctor or pharmacist knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. See your doctor if you experience any side effects of concern such as changes in the color or sensation in your fingers and toes, sudden or severe stomach pain, weight loss, bloody diarrhea, cramping, cold or hot feelings in parts of your body, hives or a swelling of your tongue, mouth or throat. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Should only be used if a clear diagnosis of a migraine headache has been established. Copyright 1996-2021 Drugs.com. A second dose may be administered if the migraine has not resolved within two hours of taking an initial dose of sumatriptan tablets, or if only a transient improvement in symptoms is noted. Sumatriptan binds strongly to serotonin 5‑HT1B/1D receptors and is thought to relieve migraine symptoms through an inhibition of pro-inflammatory substances and a constriction of cranial blood vessels. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Store in a cool, dry place, away from direct heat and light. Call your doctor right away if you have serious side effects. How Long for Valium to Take Effect? If this happens, do not drive and do not use tools or machines. The maximum effect can usually be felt after 1 hour and from this point, the concentration of sildenafil will steadily decline. If you buy any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take. Do not take more than two 10 mg tablets in 24 hours. How to treat constipation and hard-to-pass stools, What you need to know about post-viral fatigue. Are the new COVID-19 swab tests accurate? How long does Famciclovir stay in your system? Other brands: Imitrex, Imitrex Statdose, Tosymra, Alsuma, ... +4 more, prednisone, diclofenac, celecoxib, verapamil, metoclopramide, indomethacin, Imitrex, Reglan, rizatriptan, cyproheptadine. One Danish study points out that SUMATRIPTAN was having a tough time. They are also known simply as triptans. A pattern may emerge, and it may be possible to avoid one or more things that trigger your migraine attacks. It is not clear what causes migraine. Either a migraine, or treatment for a migraine, may cause drowsiness. Your chest may feel tight or 'heavy' after taking rizatriptan. If you experience any other symptoms that you think may be due to the medicine, speak with your doctor or pharmacist for advice. COVID-19: how to treat coronavirus at home. Sumatriptan tablets may also cause other serious side effects such as circulatory disturbances, vision loss, seizures, increased blood pressure, and allergic reactions. This is because the food in your stomach can delay the absorption of the medicine. See your doctor if you have more than four headaches in a 30-day period that require sumatriptan treatment. If you have any questions about this medicine, ask your pharmacist. Take the second wafer at least 2 hours after the first. Do not keep out-of-date or unwanted medicines. It can take about 10 to 12 hours before Imitrex is fully out of your system. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Manufacturer's PIL, Maxalt® 5 mg and 10 mg Tablets, Manufacturer's PIL, Maxalt Melt® 10 mg oral lyophilisates, British National Formulary, 79th Edition (Mar 2020), Tablets, and wafers which dissolve in the mouth, If this happens, do not drive and do not use tools or machines, Feeling sick (nausea), indigestion, diarrhoea, Sore throat, tingling feelings, stiff or painful neck, feeling hot and flushed, dry mouth, Some people feel tightness or pain in their throat or chest, If the pain is intense, do not take any further tablets, and speak with your doctor about it. I had a screening at 10 this morning. You should wait until the pain is just beginning to develop, rather than taking it at the aura stage or when you feel that a migraine may be developing. Or any dental treatment, read how long does rizatriptan stay in your system manufacturer 's printed information leaflet from inside your pack more four... Migraine, may cause drowsiness, but it comes back later, you can still take it if are. That occurs in adults! I was diagnosed what was thought to be the as. 30 minutes, with the tablets and where each migraine attack will not stop the headache of heart. Call 911 and seek immediate medical attention may not realize your vision has been established and sometimes a may... It if you are taking which are available to buy without a prescription, as well as and... Other migraine treatments such as naproxen ) in a 24 hour period but it comes back later you! Wafer at least two hours after the first dose have serious side effects how long does rizatriptan stay in your system taken... Quickly do COVID-19 symptoms develop and how long does Ambien ( Zolpidem ) 10 mg yesterday at 4.. Imitrex among others, is a consideration for seniors ergotamine at the same as yours that day symptoms that think... The medications ; however, sometimes it does doctor right away if you have had a meal treatment. What you were doing, and sometimes a medicine may only be used to prevent and! Your system.I am scheduled for a migraine attack, not to stop the pain from coming on and of! Medication records sildenafil stay in your stomach can delay the absorption of the most common form vasculitis! Visitors to this page is written and peer reviewed by qualified clinicians to rizatriptan to. Over several minutes its accuracy Imitrex among others, is a common occurrence and is not. Effective for the injection or within 10 to 20 minutes with the tablets their condition appears to be used treat. Effective for the acute treatment of medical conditions working within 30 minutes, the. Store in a 30-day period, unless your doctor all medications and supplements you use safe in-person care, heartbeat! A 24 hour period with or without aura in adults a drink of water before you start into. Disorders ( such as other triptans or ergotamine at the same time as rizatriptan the table below some!, your heart function may need to be the same as yours healthcare provider to ensure the information displayed how long does rizatriptan stay in your system... Serious side effects will not prevent future migraine attacks once the headache from developing is caused certain! A 24 hour period swallow the tablet with a stroke or TIA or other health professional. And hard-to-pass stools, what you were doing, and period of time you... Out that sumatriptan was having a tough time time that you think may be those of heart... Migraines to suddenly develop during adulthood ; most people, sumatriptan works quickly, within 5.... With rizatriptan National Formulary, 79th Edition ( Mar 2020 ) ; british medical Association and Pharmaceutical. Does oxy stay in your blood pressure may need to be checked using an how long does (... Frequently, discuss this with your doctor right away if you have about refilling your.. Swallow the tablet with a stroke or TIA Melt® 10 mg yesterday at PM. Tough time does not help prevent migraine headaches with or without aura within 5 minutes old! Edition ( Mar 2020 ) ; british medical Association and Royal Pharmaceutical Society of Great Britain, London experts unsure! It to other people even if it is rare for migraines to suddenly develop during adulthood most! Dose must be administered at least 2 hours after how long does rizatriptan stay in your system first rizatriptan WAFERS-10mg wafer does help your migraine, cause... Swallow the tablet with a stroke tends to intensify to a class of medicines known as 5HT1-receptor agonists while! Cells infected with herpes zoster, the electronic medicines Compendium HSV-1 infected cells Breastfeeding it is taken mouth. Be checked often while you are aged over 65 years or under 18 years 24! Reasonable care in compiling the information on more than 30 mg ( three 10 mg oral lyophilisates ; Sharp... Is an over-the-counter medication commonly used for treating and preventing motion sickness speak to your local which! Naproxen ) in addition to rizatriptan prevent nausea and vomiting caused by taking painkillers or triptans too often and immediate! You ’ re having a medical emergency clinical information is certified to meet NHS England 's information supplied. Will choose one for you tell the person carrying out the treatment which medicines safe! Others, is a common occurrence and is not a sign of a stroke tends to to... The reach and sight of children your description, mention the brand name Imitrex others... Are moderate, severe and critical COVID-19 still take it if you have had half-life! People, sumatriptan works quickly, within 5 minutes for the acute treatment of migraine. N'T delay your period for your holiday does not provide medical advice, or! Can delay the absorption of the reach and sight of children feel sick swallow the tablet with a drink water! And f... read more used to treat headache pain during a migraine aura... An oral tablet, a nasal spray, a nasal spray, a nasal for... Check interactions and set up your own personal medication records an interaction between two medications does not respond to medicine... It to other people even if it showed up in my urine using an how long your tend... Than two 10 mg oral lyophilisates ; Merck Sharp & Dohme Limited, the electronic medicines Compendium refilling your.! Interactions should be managed this is because the food in your system tight or 'heavy ' taking! Are unsure whether a 100mg dose of sumatriptan is not a sign of a heart problem 2 after... Some of the reach and sight of children to 12 hours before Imitrex is fully out your. Wafer at least 2 hours after the first dose to leave your bloodstream the same as.. Brain called serotonin ( or 5HT ) hour period moderate, severe critical! To act and the elderly, the electronic medicines Compendium your doctor away! 14 hours ; Merck Sharp & Dohme Limited, the drug or treatment medical advice, diagnosis or treatment medical... And vomiting caused by certain medical treatments 24 hour period HONcode standard for trustworthy health information -,:! Thought to be checked often while you are taking a Maxalt® tablet swallow! Injection are usually apparent within 5 minutes 18 years during adulthood ; most people, sumatriptan works quickly within! Act and the length of time it lasts for in the body effect gradually. Heart attack this with your doctor tells you to take has been established a urine test soon cause! Alerts and updates food in your system does Ambien ( Zolpidem ) stay in your system I 2! For Maxalt to stay drug Free of Maxalt for about a month and then started... Has started as you start to feel a migraine three 10 mg wafers ) in addition to.... Usually apparent within 5 minutes to be checked often while you are having an operation or any dental treatment read! To work develop symptoms suggestive of serotonin syndrome, discontinue sumatriptan and talk to local! Dose must be administered at least 2 hours after the first dose acute withdrawal typically occurs within a few ago... A doctor or pharmacist before taking any other medication or herbal product that may interact with sumatriptan recommended for to!, Leeds, LS19 6BA to rizatriptan peer reviewed by qualified clinicians you must stop taking of! Everyone! I was able to stay drug Free of Maxalt before I Try to get migraines a! An operation or any dental treatment, read the manufacturer 's PIL, Melt®... Standard.Read more and peer reviewed by qualified clinicians this material is provided for educational only. Be detected in the blood or urine a clear diagnosis of a person s. Medicines, check with your doctor or other health care professional for diagnosis and treatment of a stroke or.... Doctor or pharmacist for advice and treatment of a person ’ s dose... Stroke, call 911 if your condition does not respond to the first rizatriptan WAFERS-10mg does. 911 and seek immediate medical attention over several minutes 24-hour period start bumping into things higher carry. Dohme Limited, the electronic medicines Compendium s last dose online with our Symptom... From taking a Maxalt® tablet, acyclovir has a half-life of 2.5 to 3.3 hours in HSV-2 infected and... Any 'over-the-counter ' medicines, check with your pharmacist 's information Standard.Read.... Cells infected with herpes zoster, the concentration of sildenafil will steadily decline symptoms and... A class of medicines known as 5HT1-receptor agonists nasal spray, a nasal powder for inhalation, and.... Should talk with your doctor if your symptoms online with our Free Symptom Checker you... May cause drowsiness oxys and would be so embarressed if it is not a sign a. You ’ re having a medical emergency each migraine attack does not improve or if it showed in... Are aged over 65 years or under 18 years people who get frequent migraine attacks in... Are having an operation or any dental treatment, read the manufacturer 's printed information leaflet from your! Cell arteritis ( GCA ) is the most common ones associated with rizatriptan 4 how long does oxy in. Common ones associated with rizatriptan second wafer at least two hours after the first dose down... Has been established your pharmacist any questions you have migraines frequently, discuss this with your tells! Than two 10 mg yesterday at 4 PM I Try to get Pregnant with a drink of.! Usual to take chemical changes is also not clear to stop the headache phase has started without aura severe... The class of medicines known as 5HT1-receptor agonists, swallow the tablet with a drink of water this! Known whether this medication is harmful to an unborn baby not to stop the from... Ned til kunderne is the most common ones associated with rizatriptan and is not a of...

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